Effects of resistance exercise training on redox homeostasis in older adults. Asystematic review and meta-analysis

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dc.contributor.authorCuyul Vásquez, Iván
dc.contributor.authorBerríos Contreras, Lily
dc.contributor.authorSoto Fuentes, Stephanie
dc.contributor.authorHunter Echeverría, Karina
dc.contributor.authorMarzuca Nassr, Gabriel
dc.coverageChileen_US
dc.date2020-06-16
dc.date.accessioned2024-03-20T18:42:45Z
dc.date.available2024-03-20T18:42:45Z
dc.description.abstractBackground Resistance exercise training (RET) has proven effective at reducing the risk of chronic disease in older populations, and it appears to regulate redox homeostasis. Aims To determine the effects of RET on redox homeostasis in older people. Study design A systematic review and meta-analysis of randomized clinical trials identified by searching MEDLINE, Web of Science, EMBASE, Sportdiscus, LILACS, CENTRAL and CINAHL. We included studies of subjects aged 65 years or older, with or without pathologies, and including RET metrics with quantified molecular oxidation and antioxidant capacity outcomes. Results Fifteen studies were included in this review. Agreement between reviewers reached a kappa value of 0.725. There were a total of 614 participants, with an average age of 68.1 years. Five (for molecular oxidation markers) and three (for antioxidant capacity markers) studies included data that quantified the effects of RET on homeostasis redox. The results of the meta-analysis showed that there were no differences in the molecular oxidation markers (SMD = −0.26; 95% CI = −0.57 to 0.05; P = 0.10; I2 = 0%) and antioxidant capacity markers (SMD = 0.53; 95% CI = −0.20 to 1.26; P = 0.16; I2 = 71.5%) in healthy older people after a RET of 8–24 weeks compared to non-intervention. Conclusions Based on a small number of studies of low methodological quality, this systematic review with meta-analysis suggests that RET is not effective at reducing molecular oxidation markers in healthy older people. More research is needed on the effects of RET on redox homeostasis in older people.en_US
dc.description.versionpostprinten_US
dc.formatPDFen_US
dc.identifier.citationExperimental Gerontology, Vol. 138, 2020, 111012en_US
dc.identifier.doi10.1016/j.exger.2020.111012en_US
dc.identifier.issn0531-5565en_US
dc.identifier.urihttps://repositoriodigital.uct.cl/handle/10925/5558
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE LTDen_US
dc.rightsTodos los derechos reservadosen_US
dc.sourceExperimental Gerontologyen_US
dc.subjectResistance exercise trainingen_US
dc.subjectAging
dc.subjectOxidative stress
dc.subjectAntioxidants
dc.titleEffects of resistance exercise training on redox homeostasis in older adults. Asystematic review and meta-analysisen_US
dc.typeArtículo de Revistaen_US
uct.carreraKinesiologíaen_US
uct.catalogadorJCCLen_US
uct.comunidadCiencias de la Saluden_US
uct.disciplinaKinesiologíaen_US
uct.facultadFacultad de Ciencias de la Saluden_US
uct.indizacionSCI EXPANDEDen_US
uct.indizacionDOAJ
uct.indizacionSCOPUS
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