Hybrid porous silicon/green synthetized Ag microparticles as potential carries for Ag nanoparticles and drug delivery
Hybrid porous silicon/green synthetized Ag microparticles as potential carries for Ag nanoparticles and drug delivery
Authors
Hernandez Montelongo, Jacobo
Fernandez Fierro, Cristian
Benito Gomez, Noelia
Romero Saez, Manuel
Parodi Rivera, Jorge
Carmona Ortíz, Erico
Recio Sánchez, Gonzalo
Fernandez Fierro, Cristian
Benito Gomez, Noelia
Romero Saez, Manuel
Parodi Rivera, Jorge
Carmona Ortíz, Erico
Recio Sánchez, Gonzalo
Authors
Date
Datos de publicación:
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,Vol.116,,2020
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Abstract
In the present work, the fabrication of hybrid porous silicon/green synthetized Ag microparticles was shown and the potential use as carriers for Ag nanoparticles and drug delivery was explored. Hybrid microparticles were fabricated by incorporating green synthetized Ag nanoparticles into porous silicon matrix. The main physicochemical characteristics of the hybrid systems were studied by several techniques including UV-vis spectroscopy, TEM, SEM, XRD and XPS. The toxicology of these hybrid systems was investigated by cell viability, MTT, and comet assays. In addition, the possibility to aggregate different drug to use as drug delivery system was demonstrated by using florfenicol as drug model, due to its importance in salmon industry. The experimental results showed the potential to use these hybrid systems as carries for drug delivery in salmon industry.