Hybrid porous silicon/green synthetized Ag microparticles as potential carries for Ag nanoparticles and drug delivery

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dc.contributor.authorHernandez Montelongo, Jacobo
dc.contributor.authorFernandez Fierro, Cristian
dc.contributor.authorBenito Gomez, Noelia
dc.contributor.authorRomero Saez, Manuel
dc.contributor.authorParodi Rivera, Jorge
dc.contributor.authorCarmona Ortíz, Erico
dc.contributor.authorRecio Sánchez, Gonzalo
dc.date2020
dc.date.accessioned2021-04-30T17:05:06Z
dc.date.available2021-04-30T17:05:06Z
dc.description.abstractIn the present work, the fabrication of hybrid porous silicon/green synthetized Ag microparticles was shown and the potential use as carriers for Ag nanoparticles and drug delivery was explored. Hybrid microparticles were fabricated by incorporating green synthetized Ag nanoparticles into porous silicon matrix. The main physicochemical characteristics of the hybrid systems were studied by several techniques including UV-vis spectroscopy, TEM, SEM, XRD and XPS. The toxicology of these hybrid systems was investigated by cell viability, MTT, and comet assays. In addition, the possibility to aggregate different drug to use as drug delivery system was demonstrated by using florfenicol as drug model, due to its importance in salmon industry. The experimental results showed the potential to use these hybrid systems as carries for drug delivery in salmon industry.
dc.identifier.citationMATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,Vol.116,,2020
dc.identifier.doi10.1016/j.msec.2020.111183
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/3966
dc.language.isoen
dc.publisherELSEVIER
dc.sourceMATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
dc.subject.englishPorous silicon
dc.subject.englishGreen synthesis
dc.subject.englishSilver nanoparticles
dc.subject.englishDrug delivery
dc.titleHybrid porous silicon/green synthetized Ag microparticles as potential carries for Ag nanoparticles and drug delivery
dc.typeArticle
uct.catalogadorWOS
uct.indizacionSCI
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