Muscle Quality Index in Morbidly Obesity Patients Related to Metabolic Syndrome Markers and Cardiorespiratory Fitness

datacite.alternateIdentifier.citationNUTRIENTS,Vol.15,,2023
datacite.alternateIdentifier.doi10.3390/nu15112458
datacite.creatorCaamano Navarrete, Felipe
datacite.creatorJerez Mayorga, Daniel
datacite.creatorAlvarez, Cristian
datacite.creatordel Cuerpo, Indya
datacite.creatorCresp Barria, Mauricio
datacite.creatorDelgado Floody, Pedro
datacite.date2023
datacite.subject.englishmuscle quality index
datacite.subject.englishfitness
datacite.subject.englishsevere obesity
datacite.subject.englishmetabolic syndrome
datacite.titleMuscle Quality Index in Morbidly Obesity Patients Related to Metabolic Syndrome Markers and Cardiorespiratory Fitness
dc.date.accessioned2023-07-11T23:44:08Z
dc.date.available2023-07-11T23:44:08Z
dc.description.abstractBackground: Muscle quality index (MQI) is an emerging health indicator obtained by dividing handgrip strength by body mass index (BMI) that needs to be studied in morbidly obese patients (defined by BMI >= 35 kg/m(2)). Objective: To determine the association between MQI, metabolic syndrome (MetS) markers, and cardiorespiratory fitness (CRF), and as a second objective to determine the potential mediation role of MQI in the relationship between abdominal obesity and systolic blood pressure (SBP) in this sample. Methods: This cross-sectional study included 86 severely/morbidly obese patients (age = 41.1 +/- 11.9 y, nine men). MQI, metabolic syndrome markers, CRF, and anthropometric parameters were measured. Two groups were developed according to MQI; High-MQI (n = 41) and Low-MQI (n = 45). Results: The Low-MQI group reported higher abdominal obesity (High-MQI: 0.7 +/- 0.1 vs. Low-MQI: 0.8 +/- 0.1 WC/height; p = 0.011), SBP (High-MQI: 133.0 +/- 17.5 vs. Low-MQI: 140.1 +/- 15.1 mmHg; p = 0.048), and lower CRF (High-MQI; 26.3 +/- 5.9 vs. Low-MQI; 22.4 +/- 6.1 mL/kg/min, p = 0.003) than the High-MQI group. Waist-to-height ratio (beta: -0.07, p = 0.011), SBP (beta: -18.47, p = 0.001), and CRF (beta: 5.21, p = 0.011) were linked to MQI. In a mediation model, the indirect effect confirms that MQI is a partial mediator of the association between abdominal obesity with SBP. Conclusions: MQI in morbidly obesity patients reported an inverse association with MetS markers and a positive association with CRF (VO2(max)). It mediates the relationship between abdominal obesity and SBP.
dc.identifier.urihttps://repositoriodigital.uct.cl/handle/10925/5383
dc.language.isoen
dc.publisherMDPI
dc.sourceNUTRIENTS
oaire.resourceTypeArticle
uct.indizacionSCI
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