Strategy for biological co-production of levulinic acid and polyhydroxyalkanoates by using mixed microbial cultures fed with synthetic hemicellulose hydrolysate

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dc.contributor.authorPinto Ibieta, F.
dc.contributor.authorCea, M.
dc.contributor.authorCabrera, F.
dc.contributor.authorAbanto, M.
dc.contributor.authorFelissia, F. E.
dc.contributor.authorArea, M. C.
dc.contributor.authorCiudad, G.
dc.date2020
dc.date.accessioned2021-04-30T16:59:14Z
dc.date.available2021-04-30T16:59:14Z
dc.description.abstractHemicellulose hydrolysates (HH), which could be an interesting carbon source to feed mixed microbial cultures (MMC) able to accumulate high value-added compounds. This research focused on the evaluation of a culture strategy to achieve the simultaneous biological production of Levulinic Acid (LA) and Polyhydroxyalcanoates (PHA) by MMC fed with a synthetic HH (SHH). The culture strategy involves the use of sequential batch reactors (SBR) to select microorganisms capable of producing LA and PHA. This work proved that the cultivation strategy used allowed the biological production of LA, reaching 37%w/w when the SHH was composed of 85% pentoses. In addition, the simultaneous biological production of LA and PHB was possible when the SHH was enriched with acetate (45% pentoses - 50% acetate). Finally, this study showed that the composition of the SHH impacts directly on the selected microorganism genus and the type and quantity of the value-added compounds obtained.
dc.identifier.citationBIORESOURCE TECHNOLOGY,Vol.309,,2020
dc.identifier.doi10.1016/j.biortech.2020.123323
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/3754
dc.language.isoen
dc.publisherELSEVIER SCI LTD
dc.sourceBIORESOURCE TECHNOLOGY
dc.subject.englishLevulinic acid biological production
dc.subject.englishPolyhydroxyalkanoates and levulinic acid co-production
dc.subject.englishMixed microbial cultures
dc.subject.englishHemicellulose hydrolysate
dc.titleStrategy for biological co-production of levulinic acid and polyhydroxyalkanoates by using mixed microbial cultures fed with synthetic hemicellulose hydrolysate
dc.typeArticle
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