Avances en la rehabilitación auditiva con células madre
Avances en la rehabilitación auditiva con células madre
Authors
Yévenes Briones, Humberto
Picó Berenguer, Marusela
Oñate Parra, Pablo
Picó Berenguer, Marusela
Oñate Parra, Pablo
Authors
Date
Datos de publicación:
10.1016/j.rlfa.2019.03.001
Keywords
Células madre - Pérdida de la audición - Rehabilitación - Oído interno
Collections
Abstract
Según la Organización Mundial de la Salud en el mundo hay 360 millones de personas que sufren algún tipo de pérdida auditiva discapacitante. Actualmente los tratamientos más usados para la rehabilitación de hipoacusias neurosensoriales son los aparatos electrónicos como audífonos o dispositivos implantables, tanto cocleares como osteointegrados. La presente revisión resume los avances que se han producido en la rehabilitación auditiva con células madre, y cómo éstas contribuyen en la generación de nuevas células ciliadas y neuronas auditivas. También se revisa el uso combinado con implantes cocleares, y cómo este último ayuda a la creación de redes entre las células ciliadas y las neuronas auditivas.
Si bien queda un largo camino por recorrer y poder resolver algunos problemas como la implantación en la cóclea o ganglio espiral de las células o neuronas creadas exógenamente, este tipo de terapia abre una solución para una rehabilitación auditiva que en muchos casos supondría la solución definitiva para la discapacidad auditiva.
There are 360 million people who suffers some kind of Hearing loss disability according to the World Health Organization (WHO). Currently, the electronic devices such as hearing aids or implantable devices both cochlear and osseointegrated, are the most useful treatments to hearing loss rehabilitation. The following review summarized both the advances that have occurred in the auditory rehabilitation with stem cells, and how they have helped in the generation of new hair cells and auditory neurons. Besides, both the combined use with cochlear implants and how it helps to create networks between the hair cells and the auditory neuron was reviewed. Although, there is a long way to go and solving some problems, such as implantation in the wall or the spiral ganglion of cells or neurons created exogenously, this kind of therapy opens a solution for a rehabilitation which would be the solution definitive for hearing impairment.
There are 360 million people who suffers some kind of Hearing loss disability according to the World Health Organization (WHO). Currently, the electronic devices such as hearing aids or implantable devices both cochlear and osseointegrated, are the most useful treatments to hearing loss rehabilitation. The following review summarized both the advances that have occurred in the auditory rehabilitation with stem cells, and how they have helped in the generation of new hair cells and auditory neurons. Besides, both the combined use with cochlear implants and how it helps to create networks between the hair cells and the auditory neuron was reviewed. Although, there is a long way to go and solving some problems, such as implantation in the wall or the spiral ganglion of cells or neurons created exogenously, this kind of therapy opens a solution for a rehabilitation which would be the solution definitive for hearing impairment.