Oral Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) formulation modified muscle fatty acid profile and cytokines transcription in head kidney in rainbow trout (Oncorhynchus mykiss) fingerlings

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datacite.alternateIdentifier.citationAQUACULTURE REPORTS,Vol.20,,2021
datacite.alternateIdentifier.doi10.1016/j.aqrep.2021.100772
datacite.creatorHerrera, Fidel
datacite.creatorVelazquez, Janet
datacite.creatorLugo, Juana Maria
datacite.creatorOrellana, Paola
datacite.creatorRuiz, Joceline
datacite.creatorVega, Matias
datacite.creatorRomero, Alex
datacite.creatorSantos, Nestor
datacite.creatorRamses, Gerardo
datacite.creatorRodriguez-Ramos, Tania
datacite.creatorDixon, Brian
datacite.creatorEstrada, Mario Pablo
datacite.creatorDantagnan, Patricio
datacite.creatorCarpio, Yamila
datacite.date2021
datacite.subject.englishDiet
datacite.subject.englishFunctional feed
datacite.subject.englishFatty acids
datacite.subject.englishImmunity
datacite.subject.englishPACAP
datacite.subject.englishRainbow trout
datacite.titleOral Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) formulation modified muscle fatty acid profile and cytokines transcription in head kidney in rainbow trout (Oncorhynchus mykiss) fingerlings
dc.date.accessioned2021-10-04T18:44:51Z
dc.date.available2021-10-04T18:44:51Z
dc.description.abstractPituitary adenylate cyclase-activating polypeptide (PACAP) is a multifunctional neuropeptide belonging to the glucagon/secretin superfamily. Its role in fish growth and immunity has been previously demonstrated using different administration routes such as injection or immersion bath. The present study evaluated the physiological effects of a new feed formulation containing Clarias gariepinus synthetic PACAP-38 administered to rainbow trout (Oncorhynchus mykiss) fingerlings. With this aim, a new oiled formulation containing the peptide was developed and two diets with different PACAP concentrations were prepared. After two months of administration, dietary supplementation with PACAP markedly improved the PUFA content in muscle, increased the total number of caliciform cells within the intestinal villi and modulated the transcription of some of the studied cytokines in head kidney. This study suggests new potential outcomes in further advancing of the use of small peptides as feed additives and formulations to improve the quality of culture fish fingerlings.
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/4283
dc.language.isoen
dc.publisherELSEVIER
dc.sourceAQUACULTURE REPORTS
oaire.resourceTypeArticle
uct.indizacionSCI
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