The Wing-Spot and the Comet Tests as Useful Assays Detecting Genotoxicity in Drosophila

Simple item page
datacite.alternateIdentifier.citationGENOTOXICITY ASSESSMENT: METHODS AND PROTOCOLS,Vol.1044,417-427,2013
datacite.alternateIdentifier.doi10.1007/978-1-62703-529-3_23
datacite.creatorMarcos, Ricard
datacite.creatorCarmona Ortíz, Erico
datacite.creatorDhawan, A
datacite.creatorBajpayee, M
datacite.date2013
datacite.subject.englishDrosophila
datacite.subject.englishGenotoxicity
datacite.subject.englishComet assay
datacite.subject.englishWing-spot test
datacite.subject.englishDNA damage
datacite.titleThe Wing-Spot and the Comet Tests as Useful Assays Detecting Genotoxicity in Drosophila
dc.date.accessioned2021-04-30T16:35:24Z
dc.date.available2021-04-30T16:35:24Z
dc.description.abstractIn spite of its pioneer use in detecting mutational processes, Drosophila has yet an important role in studies aiming to detect and quantify the induction of DNA damage. Here we describe two assays, one detecting primary damage (the Comet assay) and the other detecting somatic mutation and recombination effects (wing-spot test). It is important to emphasize that somatic recombination is a key event in cancer and no assays exist to detect and quantify somatic recombination processes, other than the spot tests developed in Drosophila.
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/3189
dc.language.isoen
dc.publisherHUMANA PRESS INC
dc.sourceGENOTOXICITY ASSESSMENT: METHODS AND PROTOCOLS
uct.catalogadorWOS
uct.indizacionBSCI
Files
Collections
Migración Web of Science