Ovulation-inducing factor (OIF/NGF) from seminal plasma origin enhances Corpus Luteum function in llamas regardless the preovulatory follicle diameter

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dc.contributor.authorSilva Jiménez, Mauricio
dc.contributor.authorUlloa Leal, C.
dc.contributor.authorNorambuena, C.
dc.contributor.authorFernandez, A.
dc.contributor.authorAdams, G. P.
dc.contributor.authorRatto, Marcelo
dc.date2014
dc.date.accessioned2021-04-30T16:58:24Z
dc.date.available2021-04-30T16:58:24Z
dc.description.abstractOvulation-inducing factor (OIF) is a protein present in llama seminal plasma that has recently been identified as beta-Nerve Growth Factor (NGF) and it induces not only a high rate of ovulation but also appears to have luteotrophic properties in this species. A 2-by-2 experimental design was used to determine the effect of treatments (OIF/NGF vs GnRH) and categories of preovulatory follicle diameter (7-10 vs >10 mm) on ovulation rate, CL diameter and function in llamas. Llamas (n = 32 llamas per group) were randomly assigned to receive an intramuscular dose of: (a) 1 mg purified OIF/NGF in the presence of a follicle of 7-10 mm in diameter: (b) 50 mu g of GnRH in the presence of a follicle of 7-10mm in diameter: (c) 1 mg purified OIF/NGF in the presence of a follicle >10 ram in diameter; (d) 50 mu g of GnRH in the presence of a follicle >10 mm in diameter. Llamas were examined by ultrasonography every 12h from treatment to Day 2 (Day 0 = treatment) to detect ovulation, and again on Day 8 to determine CL diameter. Ovulation rates did not differ among groups. There was an effect of preovulatory follicle size on Corpus Luteum diameter at Day 8 (P < 0.001), however plasma progesterone concentration (n = 15/per group) was higher (P < 0.05) in the OIF/NGF - than that of the GnRH - treated group by the same day. We conclude that OIF/NGF treatment enhances CL function regardless preovulatory follicle size at the time of treatment. (C) 2014 Elsevier B.V. All rights reserved.
dc.identifier.citationANIMAL REPRODUCTION SCIENCE,Vol.148,221-227,2014
dc.identifier.doi10.1016/j.anireprosci.2014.05.012
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/3652
dc.language.isoen
dc.publisherELSEVIER SCIENCE BV
dc.sourceANIMAL REPRODUCTION SCIENCE
dc.subject.englishLlama
dc.subject.englishOvulation-inducing factor
dc.subject.englishNerve Growth Factor
dc.subject.englishCorpus Luteum
dc.subject.englishFollicles
dc.titleOvulation-inducing factor (OIF/NGF) from seminal plasma origin enhances Corpus Luteum function in llamas regardless the preovulatory follicle diameter
dc.typeArticle
uct.catalogadorWOS
uct.indizacionSCI
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