Risk of Global Developmental Delay in Infants Born from Mothers with COVID-19: A Cross-Sectional Study

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datacite.alternateIdentifier.citationINTERNATIONAL JOURNAL OF WOMENS HEALTH,Vol.15,467-474,2023
datacite.alternateIdentifier.doi10.2147/IJWH.S389291
datacite.creatorSilva, Pedro Ykaro Fialho
datacite.creatorda Cruz, Maria Clara Lima
datacite.creatorAzevedo, Ingrid Guerra
datacite.creatorMoreira, Rafaela Silva
datacite.creatorSousa, Klayton Galante
datacite.creatorPereira, Silvana Alves
datacite.date2023
datacite.subject.englishinfant development
datacite.subject.englishCOVID-19
datacite.subject.englishinfant well-being
datacite.titleRisk of Global Developmental Delay in Infants Born from Mothers with COVID-19: A Cross-Sectional Study
dc.date.accessioned2023-06-08T15:48:14Z
dc.date.available2023-06-08T15:48:14Z
dc.description.abstractPurpose: To investigate the risk of global developmental delay in infants born from mothers with COVID-19.Patients and Methods: A cross-sectional study was conducted between March and November 2021, with 54 infants of both sexes aged between 1 and 12 months. Twenty-seven infants born from mothers diagnosed with COVID-19 during pregnancy composed the COVID-19 group, whereas infants born from mothers not exposed to COVID-19 composed the control group. Medical records and child health booklets provided neonatal and prenatal data. The Survey of Wellbeing of Young Children screened the risk of global developmental delay during a phone interview or home visit. Chi-squared, Mann-Whitney test, and binary logistic regression were applied.Results: The risk of motor developmental delay was identified in 15 infants (12 in the COVID-19 group), while 36 were at risk of behavioral alteration (22 in the COVID-19 group). The COVID-19 group presented a 6.3-fold risk of motor developmental delay. Motor developmental delay was also significantly associated with socioemotional alterations (odds ratio = 6.4, p = 0.01). Regarding families of infants in the COVID-19 group, 63% of the mothers presented risk of depression, 51.9% risk of substance abuse, 40.7% risk of food insecurity, and 7.4% risk of domestic violence. The inflexibility subscale of the survey was a statistically relevant variable for the socioemotional domain.Conclusion: Infants born from mothers with COVID-19 were at high risk of motor developmental delay and socioemotional alterations. Although, this study fills an important gap in the literature regarding the influence of maternal exposure to COVID-19 on infant development, new studies screening families with infants at risk of developmental delay may significantly impact maternal and child health-related indicators, such as physical health, emotional development and social behavior.
dc.identifier.urihttps://repositoriodigital.uct.cl/handle/10925/5299
dc.language.isoen
dc.publisherDOVE MEDICAL PRESS LTD
dc.sourceINTERNATIONAL JOURNAL OF WOMENS HEALTH
oaire.resourceTypeArticle
uct.indizacionSCI
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