Membranoproliferative glomerulonephritis possibly associated with over-vaccination in a cocker spaniel

dc.contributor.authorOrtloff Trautmann, Alexander
dc.contributor.authorMorán, G.
dc.contributor.authorOlavarría, A.
dc.contributor.authorFolch, H.
dc.date2010
dc.date.accessioned2012-02-08T20:45:53Z
dc.date.available2012-02-08T20:45:53Z
dc.date.issued2012-02-08
dc.description.abstractMembranoproliferative glomerulonephritis was observed in a seven-month-old male cocker spaniel dog. The clinical, microbiological, biochemical, radiographic and ultrasonographic examinations ruled out neoplasia, congenital disease and infectious disease. The anamnesis revealed that the owner had vaccinated the dog seven times, one vaccination per month, without veterinarian supervision. In both kidneys, severe thickening of the glomerular capillary walls was observed. Electron microscope examination revealed a large number of electron-dense deposits that were primarily in the glomerular subendothelial spaces and the basal membrane, which is compatible with antigen-antibody complexes. The immunohistochemical examination revealed that the antigen present in the glomeruli corresponded with the antigen present in the vaccine. We report a type III hypersensitivity nephropathy in a young dog, which was possibly caused by over-vaccination. © 2010 British Small Animal Veterinary Association.es
dc.formatPDFes
dc.identifier.citationJournal of Small Animal Practice, Vol. 51, N°9, 499-502, 2010es
dc.identifier.doi10.1111/j.1748-5827.2010.00978.xes
dc.identifier.urihttps://hdl.handle.net/10925/610
dc.language.isoenes
dc.sourceJournal of Small Animal Practicees
dc.subjectAnimaleses
dc.subjectEnfermedades de perroses
dc.subjectGlomerulonefritises
dc.titleMembranoproliferative glomerulonephritis possibly associated with over-vaccination in a cocker spanieles
dc.typeArtículo de Revistaes
uct.carreraAgronomíaes
uct.carreraMedicina Veterinariaes
uct.catalogadoragaes
uct.comunidadRecursos Naturaleses
uct.facultadFacultad de Recursos Naturaleses
uct.indizacionISIes
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