GnRHa treatments of Atlantic Salmon broodstock suppresses effects of endocrine disruptors, benefitting offspring quality

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datacite.alternateIdentifier.citationAnimal Reproduction Science, 217, 2020
datacite.alternateIdentifier.doi10.1016/j.anireprosci.2020.106470
datacite.alternateIdentifier.issn0378-4320
datacite.creatorZepeda, Andrea B.
datacite.creatorMiranda, Ignacia B.
datacite.creatorValdebenito, Iván
datacite.creatorMoreno, Ricardo D.
datacite.creatorFarias, Jorge G.
datacite.date2020
datacite.rightsRegistro bibliográfico
datacite.subjectEndocrine Disruptor
datacite.subjectGnrha
datacite.subjectMalformations
datacite.subjectSalmo Salar
datacite.subjectEstradiol
datacite.subjectGonadorelin
datacite.subjectTestosterone
datacite.subjectEndocrine Disruptors
datacite.subjectEstradiol
datacite.subjectGonadotropin-releasing Hormone
datacite.subjectLhrh, Ala(6)-gly(10)-ethylamide-
datacite.subjectTestosterone
datacite.subjectWater Pollutants, Chemical
datacite.subjectEndocrine Disruptor
datacite.subjectEstradiol
datacite.subjectGonadorelin
datacite.subjectLhrh, Ala(6)-gly(10)-ethylamide-
datacite.subjectTestosterone
datacite.subjectAnimal
datacite.subjectAquaculture
datacite.subjectBlood
datacite.subjectDrug Effect
datacite.subjectEmbryology
datacite.subjectFemale
datacite.subjectFish Disease
datacite.subjectLarva
datacite.subjectMale
datacite.subjectSalmo Salar
datacite.subjectToxicity
datacite.subjectWater Pollutant
datacite.subjectAnimals
datacite.subjectAquaculture
datacite.subjectEndocrine Disruptors
datacite.subjectEstradiol
datacite.subjectFemale
datacite.subjectFish Diseases
datacite.subjectGonadotropin-releasing Hormone
datacite.subjectLarva
datacite.subjectMale
datacite.subjectTestosterone
datacite.subjectWater Pollutants, Chemical
datacite.titleGnRHa treatments of Atlantic Salmon broodstock suppresses effects of endocrine disruptors, benefitting offspring quality
dc.contributor.authorFIGUEROA VILLALOBOS, ELIAS GUSTAVO
dc.date.accessioned2025-10-06T14:21:39Z
dc.date.available2025-10-06T14:21:39Z
dc.description.abstractThe use of synthetic hormones to regulate sexual maturity in captive fish is a common practice. With aquaculture practices, fish production is desired throughout the year, necessitating the maintenance of quality standards, mainly regarding the characteristics of the fish produced. Embryonic development may be affected by toxins in the environment and by a variety of pathologies. The aim of this study was to determine the effects of treatment with gonadotropin-releasing hormone analog (GnRHa) on captive male and female Atlantic Salmon (Salmo salar) broodstock, observing the effects on the hormonal milieu and impacts on breeding outcomes. Sexually mature fish were fertilized with and without imposing a GnRHa treatment to evaluate the development of offspring up to the fry stage. The concentrations of 17?-estradiol (E2) and testosterone (T) were determined using commercially available ELISA kits. The results indicate the administration of GnRHa had marked effects on reductions of morphological deformities in the offspring and promoted development during the larval stage by inducing sexual maturity in both treated parents. The E2/T ratio results indicate the presence of endocrine disruptors. It is concluded that the use of GnRHa at a dose of 10 ug/kg in captive male and female Atlantic salmon broodstock has an inhibitory effect on the impacts of endocrine disruptors, does not affect fertilization rate, and has positive effects on development of offspring by reducing the number of morphological deformities during the larval stage of development. © 2020 Elsevier B.V., All rights reserved.
dc.description.ia_keyworddevelopment, effects, gnrha, fish, offspring, captive, atlantic
dc.identifier.issn1873-2232
dc.identifier.urihttps://repositoriodigital.uct.cl/handle/10925/6721
dc.language.isoen
dc.publisherElsevier BV
dc.relationinstname: ANID
dc.relationreponame: Repositorio Digital RI2.0
dc.rights.driverinfo:eu-repo/semantics/openAccess
dc.sourceAnimal Reproduction Science
dc.subject.ia_odsODS 5: Igualdad de género
dc.subject.ia_oecd1nCiencias Naturales
dc.subject.ia_oecd2nCiencias Biológicas
dc.subject.ia_oecd3nCiencias del Medio Ambiente
dc.type.driverinfo:eu-repo/semantics/article
dc.type.driverhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.type.openaireinfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublication
oaire.citationEdition2020
oaire.citationTitleAnimal Reproduction Science
oaire.citationVolume217
oaire.fundingReferenceCONICYT ANID FONDECYT 3170193 (Postdoctorado)
oaire.fundingReferenceANID FONDECYT 1180387 (Regular)
oaire.licenseConditionCopyright © Elsevier Inc, 2020
oaire.resourceTypeArtículo
oaire.resourceType.enArticle
relation.isAuthorOfPublication9cc0cf1e-6725-4539-8f65-58f2c6a85700
relation.isAuthorOfPublication.latestForDiscovery9cc0cf1e-6725-4539-8f65-58f2c6a85700
uct.catalogadorjvu
uct.comunidadRecursos Naturalesen_US
uct.departamentoDepartamento de Ciencias Agropecuarias y Acuícolas
uct.facultadFacultad de Recursos Naturales
uct.indizacionScience Citation Index Expanded - SCIE
uct.indizacionScopus|PubMed
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