Impairment of the Functional Status and Decrease in Albumin in Frail Older People After a COVID-19 Outbreak: A Descriptive Study in a Long-Term Care Facility in Chile

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datacite.alternateIdentifier.citationGeriatrics, 10 (1), 1-1, 2024
datacite.alternateIdentifier.doi10.3390/geriatrics10010001
datacite.alternateIdentifier.issn2308-3417
datacite.creatorCastillo-Mariqueo, Lidia
datacite.creatorAedo Lagos, Alejandro
datacite.creatorGiménez-Llort, Lydia
datacite.creatorGuzmán, Neftalí
datacite.date2024
datacite.rightsAcceso Abierto
datacite.subjectCOVID-19
datacite.subjectDiscapacidad
datacite.subjectFragilidad
datacite.subjectFuncionalidad
datacite.subjectSARS-CoV-2
datacite.subjectFunción fisiológica
datacite.subjectATC
datacite.subject.englishCOVID-19
datacite.subject.englishDisability
datacite.subject.englishFrailty
datacite.subject.englishFunctionality
datacite.subject.englishSARS-CoV-2
datacite.subject.englishPhysiological function
datacite.subject.englishLTC
datacite.titleImpairment of the Functional Status and Decrease in Albumin in Frail Older People After a COVID-19 Outbreak: A Descriptive Study in a Long-Term Care Facility in Chile
dc.date.accessioned2025-08-06T18:22:42Z
dc.date.available2025-08-06T18:22:42Z
dc.description.abstractIntroduction. Frailty is a common condition among older individuals and is associated with increased vulnerability to adverse health outcomes. The COVID-19 pandemic further highlighted the impact of viral infections on frail populations. The present work aimed to determine frailty, functional and cognitive status, and clinical analysis of older persons in a long-term care facility in Chile, before and following the outbreak of COVID-19. Methods. A single-center, pre-post, and Pearson's correlational study was conducted in a cohort of 20 persons positive for COVID-19 from a total of 45 residents. Data on demographic, clinical, functional (Barthel Index (BI) and Katz) and cognitive (Mini mental Examination) status, and physiological function (hematology, lipidic and biochemical profiles) were collected. Results. The mean age was 84 ± 2.4 years, and 80% were females. The most common comorbidities were Arterial Hypertension, Diabetes Mellitus type II, and Alzheimer's disease. Physical frailty was confirmed by body weight, body mass index, and calf circumference. Pre-infection, BI was negatively correlated with lipidic profile and erythrocyte sedimentation rate (ESR), and positively with frailty (calf circumference). Pre-post analysis showed that frailty and most analytical results were not modified. However, functional dependence on daily live activities significantly increased as measured by BI, with worse grooming and bowel and bladder controls. Post-infection, correlations were lost except between BI and ESR, and decreased albumin levels were found. Conclusions. The worsening of specific functional limitations emphasizes the need for targeted interventions that can be correlated with ESR. Albumin appears as a potential biomarker for physiological dysfunction associated with their infectious/inflammatory processes.
dc.formatPDF
dc.identifier.issn2308-3417
dc.identifier.urihttps://repositoriodigital.uct.cl/handle/10925/6510
dc.language.isoen
dc.publisherMultidisciplinary Digital Publishing Institute - MDPI
dc.rightsObra bajo licencia Creative Commons Atribución 4.0 Internacional
dc.rights.licensehttps://creativecommons.org/licenses/by/4.0/
dc.sourceGeriatrics
dspace.entity.typePublication
oaire.citationEdition2024
oaire.citationEndPage1
oaire.citationIssue1
oaire.citationStartPage1
oaire.citationTitleGeriatrics
oaire.citationVolume10
oaire.fundingReferenceVicerrectoría de Investigación y Posgrado, Universidad Católica de Temuco - VIPUCT
oaire.resourceTypeArtículo
oaire.resourceType.enArticle
uct.catalogadorjvu
uct.comunidadCiencias de la Saluden_US
uct.departamentoDepartamento de Procesos Terapéuticos
uct.facultadFacultad de Ciencias de la Salud
uct.indizacionScience Citation Index Expanded - SCIE
uct.indizacionSCOPUS
uct.indizacionWOS
uct.indizacionDOAJ
uct.indizacionPubMed
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