Zebrafish as a useful model for immunological research with potential applications in aquaculture

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datacite.alternateIdentifier.citationReviews in Aquaculture, 10 (1), 223-213, 2018
datacite.alternateIdentifier.doi10.1111/raq.12156
datacite.alternateIdentifier.issn1753-5123
datacite.creatorLee-Estevez, Manuel
datacite.creatorFigueroa, Elias
datacite.creatorCosson, Jacky
datacite.creatorShort, Stefania E.
datacite.creatorValdebenito, Ivan
datacite.creatorUlloa-Rodriguez, Patricio
datacite.creatorFarias, Jorge G.
datacite.date2018
datacite.rightsRegistro bibliográfico
datacite.subjectaquaculture
datacite.subjectimmune response
datacite.subjectmucosal immunity
datacite.subjectmucosal vaccination
datacite.subjectZebrafish
datacite.titleZebrafish as a useful model for immunological research with potential applications in aquaculture
dc.contributor.authorFIGUEROA VILLALOBOS, ELIAS GUSTAVO
dc.contributor.authorVALDEBENITO ISLER, NEMESIO IVAN
dc.description.abstractThe Zebrafish (Danio Rerio) is a Teleost fish, which offers several practical advantages concerning manipulation, maintenance and versatility as well as short life cycle, low cost and physiological similarity with most farmed species. Zebrafish have been used as model for several aquaculture-relevant infectious agents, since the cost of infections to aquaculture can be great, making failure of immunity a major risk for commercial fish farming. This have allowed scientist to understand pathogens biology as well as fish immune response against infection, and thus have helped to improve disease control in aquaculture. This review summarizes the recent reports and main knowledge concerning the cellular and molecular aspects of the immune response in zebrafish and its potential applications in the fish farming industry. Several research results in zebrafish and other teleosts reveal that mucosal tissues have a strong and well-structured immune response involving both innate and adaptive components. Together with the advantages of low maintenance cost, easy handling and genetic tools available, zebrafish comes up as a useful and reliable animal model for invivo study of fish immune response and mechanisms as well as fish-affecting infectious and inflammatory diseases which are a cause of concern for the aquaculture industry. Also, vaccines development, drugs screening and immunologically focused fish food assessment seem to be promising fields where zebrafish model can be used to generate positive impacts to the aquaculture practice.
dc.description.ia_keywordzebrafish, fish, aquaculture, well, model, immune, response
dc.identifier.issn1753-5131
dc.identifier.urihttps://repositoriodigital.uct.cl/handle/10925/3577
dc.language.isoen
dc.publisherWiley
dc.relationinstname: ANID
dc.relationreponame: Repositorio Digital RI2.0
dc.rights.driverinfo:eu-repo/semantics/openAccess
dc.sourceReviews in Aquaculture
dc.subject.ia_odsODS 3: Salud y bienestar
dc.subject.ia_oecd1nCiencias Naturales
dc.subject.ia_oecd2nCiencias Biológicas
dc.subject.ia_oecd3nBiología General
dc.type.driverinfo:eu-repo/semantics/article
dc.type.driverhttp://purl.org/coar/resource_type/c_2df8fbb1
dc.type.openaireinfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublication
oaire.citationEdition2018
oaire.citationEndPage223
oaire.citationIssue1
oaire.citationStartPage213
oaire.citationTitleReviews in Aquaculture
oaire.citationVolume10
oaire.fundingReferenceANID FONDECYT 1151315 (Regular)
oaire.fundingReferenceMEC-CONICYT PAI 80160036
oaire.fundingReferenceCzech Ministry of Education CENAKVA CZ.1.05/2.1.00/01.0024, CENAKVA II LO1205, COST LD14119
oaire.fundingReferenceGrant Agency USB 114/2013/Z
oaire.fundingReferenceCzech Science Foundation P502/15-12034S
oaire.fundingReferenceCOST FA1205 AQUAGAMETE
oaire.licenseConditionCopyright © Wiley Publishing Asia Pty Ltd, 2016
oaire.resourceTypeArtículo de revisión
oaire.resourceType.enReview
relation.isAuthorOfPublication9cc0cf1e-6725-4539-8f65-58f2c6a85700
relation.isAuthorOfPublicationa18558bc-bf10-4e11-9254-4d4be1564d44
relation.isAuthorOfPublication.latestForDiscovery9cc0cf1e-6725-4539-8f65-58f2c6a85700
uct.catalogadorjvu
uct.comunidadRecursos Naturalesen_US
uct.departamentoDepartamento de Ciencias Agropecuarias y Acuícolas
uct.facultadFacultad de Recursos Naturales
uct.indizacionScience Citation Index Expanded - SCIE
uct.indizacionScopus
uct.indizacionPubMed
uct.indizacionAquatic Sciences & Fisheries Abstracts
uct.indizacionCAB Abstracts
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