Potential biomarkers of DNA quality in cryopreserved fish sperm: impact on gene expression and embryonic development

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dc.contributor.authorFigueroa, Elías
dc.contributor.authorLee Estévez, Manuel
dc.contributor.authorValdebenito, Iván
dc.contributor.authorFarías, Jorge G.
dc.contributor.authorRomero, Jaime
dc.date2018
dc.date.accessioned2019-11-19T13:52:33Z
dc.date.available2019-11-19T13:52:33Z
dc.date.issued2019-11-19
dc.description.abstractSperm DNA quality and gene expression are crucial for early embryo development. Abnormal genomic processes can cause irreversible damage to totipotent cells, thereby altering the capacity for cell differentiation. Cryopreservation is a complex procedure that exposes cells to extreme conditions; it is therefore important to determine whether cryopreservation affects genomic stability. Despite this, few studies have focused on the effects of cryopreservation on the genomic stability of fish sperm. Thus, information is lacking to determine how the cryopreservation of fish sperm affects embryo quality and subsequently aquaculture. The aim of this review was to compile background information pertaining to the study of genomic stability in cryopreserved sperm. In this way, we hope to characterize more clearly the embryonic development of fish that are of biological and economic interest. We also discuss the potential use of antioxidants in cryopreservation to help preserve DNA integrity, gene expression and embryo quality. There is a current need to evaluate the use of potential biomarkers of genomic integrity to establish the effects of cryopreservation on the DNA quality of fish gametes and embryos.es_ES
dc.formatPDFes_ES
dc.identifier.citationReviews in Aquaculture, 2018
dc.identifier.doi10.1111/raq.12323es_ES
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/2090
dc.language.isoenes_ES
dc.sourceReviews in Aquaculturees_ES
dc.subjectBiomarcadoreses_ES
dc.subjectCriopreservaciónes_ES
dc.subjectExpresión Genéticaes_ES
dc.titlePotential biomarkers of DNA quality in cryopreserved fish sperm: impact on gene expression and embryonic developmentes_ES
dc.typeArtículo de Revistaes_ES
uct.catalogadormlmes_ES
uct.comunidadRecursos Naturaleses_ES
uct.disciplinaCiencias Acuáticases_ES
uct.indizacionSCOPUSes_ES
uct.nucleosNúcleo en Producción Alimentariaes_ES
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