Recurrent respiratory papillomatosis in a pediatric patient: case report

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dc.contributor.authorBenavente Muñoz, Felipe
dc.contributor.authorContreras, Marcelo
dc.contributor.authorPerferi, Giancarlo
dc.contributor.authorAzzari, Chiara
dc.contributor.authorMunoz, Mariela
dc.contributor.authorInostroza, Jaime
dc.date2017
dc.date.accessioned2021-04-30T17:05:06Z
dc.date.available2021-04-30T17:05:06Z
dc.description.abstractIntroduction: Genetic variability related to the host immune system has been proposed as one of the most influential factors in the development of diseases caused by HPV. Clinical case: We report the case of a 5-year-old child in whom chronic laryngeal papillomatosis, probably acquired vertically during labor, was detected. The diagnosis of laryngeal papillomatosis was confirmed with a biopsy after a first surgery to remove the papillomas. The Derkay classification system was used to assess the severity of papillomatosis. Biopsy genotyping was performed by demonstrating HPV-6. Later, HLADQA1*0505, -DQB1*0301, -DRB1*1101 alleles were homozygous for HLA allele typing. Conclusions: Further studies are needed to identify the most prevalent HLA alleles in the Latino population and their potential association with genetic susceptibility in Recurrent Respiratory Papillomatosis.
dc.identifier.citationREVISTA CHILENA DE PEDIATRIA-CHILE,Vol.88,393-397,2017
dc.identifier.doi10.4067/S0370-41062017000300013
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/3962
dc.language.isoen
dc.publisherSOC CHILENA PEDIATRIA
dc.sourceREVISTA CHILENA DE PEDIATRIA-CHILE
dc.subject.englishHLA-alleles
dc.subject.englishrecurrent respiratory
dc.subject.englishpapillomatosis
dc.titleRecurrent respiratory papillomatosis in a pediatric patient: case report
dc.typeArticle
uct.catalogadorWOS
uct.indizacionESCI
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