GnRHa treatments of Atlantic Salmon broodstock suppresses effects of endocrine disruptors, benefitting offspring quality

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dc.contributor.authorZepeda, Andrea B.
dc.contributor.authorMiranda, Ignacia B.
dc.contributor.authorValdebenito Isler, Iván
dc.contributor.authorMoreno, Ricardo D.
dc.contributor.authorFarias, Jorge G.
dc.date2020
dc.date.accessioned2021-04-30T16:59:16Z
dc.date.available2021-04-30T16:59:16Z
dc.description.abstractThe use of synthetic hormones to regulate sexual maturity in captive fish is a common practice. With aquaculture practices, fish production is desired throughout the year, necessitating the maintenance of quality standards, mainly regarding the characteristics of the fish produced. Embryonic development may be affected by toxins in the environment and by a variety of pathologies. The aim of this study was to determine the effects of treatment with gonadotropin-releasing hormone analog (GnRHa) on captive male and female Atlantic Salmon (Salmo solar) broodstock, observing the effects on the hormonal milieu and impacts on breeding outcomes. Sexually mature fish were fertilized with and without imposing a GnRHa treatment to evaluate the development of offspring up to the fry stage. The concentrations of 17 beta-estradiol (E2) and testosterone (T) were determined using commercially available ELISA kits. The results indicate the administration of GnRHa had marked effects on reductions of morphological deformities in the offspring and promoted development during the larval stage by inducing sexual maturity in both treated parents. The E2/T ratio results indicate the presence of endocrine disruptors. It is concluded that the use of GnRHa at a dose of 10 ug/kg in captive male and female Atlantic salmon broodstock has an inhibitory effect on the impacts of endocrine disruptors, does not affect fertilization rate, and has positive effects on development of offspring by reducing the number of morphological deformities during the larval stage of development.
dc.identifier.citationANIMAL REPRODUCTION SCIENCE,Vol.217,,2020
dc.identifier.doi10.1016/j.anireprosci.2020.106470
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/3797
dc.language.isoen
dc.publisherELSEVIER
dc.sourceANIMAL REPRODUCTION SCIENCE
dc.subject.englishEndocrine disruptor
dc.subject.englishGnRHa
dc.subject.englishMalformations
dc.subject.englishSalmo salar
dc.titleGnRHa treatments of Atlantic Salmon broodstock suppresses effects of endocrine disruptors, benefitting offspring quality
dc.typeArticle
uct.catalogadorWOS
uct.indizacionSCI
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