Aqueous and methanol extracts of Berberis darwinii H. (Berberidaceae) inhibit innate celular responses in human monocytes in vitro treated

dc.contributor.authorAlarcon, David
dc.contributor.authorParedes, Marco
dc.contributor.authorRamos, Daniela
dc.contributor.authorGonzález Alfaro, Katerina
dc.contributor.authorDíaz Harris, Ramiro
dc.contributor.authorNunez, Daniela
dc.date2014
dc.date.accessioned2021-04-30T16:46:59Z
dc.date.available2021-04-30T16:46:59Z
dc.description.abstractBerberis darwinii H is a native plant of South America, popularly referred to Michay. This species has historically been used by indigenous cultures of Chile as medicinal herb. To preliminarily assess their anti-inflammatory effects was investigated the aqueous and methanolic root extract this plant in human monocytes. The results indicated that the extracts inhibit the production of superoxide anion, the expression of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1-beta (IL-1 beta) in monocytes activated with lipopolysaccharide. This result suggests the existence of compounds with potential anti-inflammatory action in these extracts.
dc.identifier.citationBOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS,Vol.13,81-91,2014
dc.identifier.urihttp://repositoriodigital.uct.cl/handle/10925/3471
dc.language.isoes
dc.publisherUNIV SANTIAGO CHILE CASA
dc.sourceBOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS
dc.subject.englishBerberis darwinii H
dc.subject.englishmacrophage
dc.subject.englishTNF-alpha
dc.subject.englishIL-1 beta
dc.titleAqueous and methanol extracts of Berberis darwinii H. (Berberidaceae) inhibit innate celular responses in human monocytes in vitro treated
dc.typeArticle
uct.catalogadorWOS
uct.indizacionSCI
Files